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. 2016 Nov 7;11:2757–2764. doi: 10.2147/COPD.S115581

Table 3.

aORs of positive bronchodilator response at baseline for responders after at least 3 months of bronchodilator therapy

Model aOR 95% CI P-value
Model 1 2.559 1.188–5.513 0.016
Model 2 2.407 1.096–5.283 0.029
Model 3 1.984 0.871–4.520 0.103
Final model 2.298 1.067–4.951 0.034

Notes: Model 1 was adjusted for age, sex, and BMI, model 2 was additionally adjusted for pulmonary-related variables (smoking history and baseline prebronchodilator FEV1 <50% predicted), and model 3 was additionally adjusted for number of inhalers and all of the aforementioned variables. The increment of additional variables had P-values of 0.79 for comparing model 1 vs model 2 and 0.062 for comparing model 2 vs model 3. However, the P-value was 0.049 when comparing model 1 vs model 3. The final model included only significant clinical or statistical variables, which were the number of inhalers and positive BDR at baseline.

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; BMI, body mass index; FEV1, forced expiratory volume in 1 second; BDR, bronchodilator response.