Fig. 4. Effects of NOS inhibition on PAP and HPV in V/P lungs.

(A~C) Representative traces of PAP recording in the control (A), PAH-MCT (B), and PAH-CH (C) rats. A marked increase of PAP was observed in the PAH-MCT rats with the non-specific NOS inhibitor, L-NAME (100 µM). (D) Summarized results for the three groups are shown as bar graphs. ^*p<0.05, ^**p<0.01, ^***p<0.001.