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. 2016 Oct 28;20(6):641–647. doi: 10.4196/kjpp.2016.20.6.641

Fig. 5. Effect of increased flow rate in V/P lungs of the control and PAH-MCT rats.

Fig. 5

(A, B) Representative traces of responses to the serially increased flow rate in the control and PAH-MCT rats (A). In accordance with the sequentially increased flow rate (from 5 to 45 mL/min, 5 mL/min increments), PAP in the PAH-MCT rats was significantly higher (B). Upon L-NAME (100 µM) pretreatment, the rate of the PAP increase in the PAH-MCT rats was much higher than that in saline (C). *p<0.05, **p<0.01, ***p<0.001.