Table 2.
Factors associated with non-adherence to HAART: mixed logistic model, univariate and multivariate analysis (1190 visits, 727 patients)
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Number of visits (%)or median [IQR] | Number of patients | OR [95%CI] | p-value | aOR [95%CI] | p-value | |
| Female gender | 363 (31) | 224 | 0.94 [0.58–1.51] | 0.80 | ||
|
| ||||||
| Agea | 45 [42–48] | 0.76 [0.54–1.09] | 0.14 | |||
|
| ||||||
| Being employed | 581 (50) | 387 | 0.71 [0.47–1.08] | 0.11 | ||
|
| ||||||
| Having children | 366 (31) | 247 | 0.99 [0.62–1.57] | 0.96 | ||
|
| ||||||
| High school certificate | 321 (31) | 185 | 0.73 [0.43–1.23] | 0.24 | ||
|
| ||||||
| Living in a couple | 567 (48) | 368 | 0.69 [0.45–1.06] | 0.09 | ||
|
| ||||||
| Comfortable housing | 994 (84) | 630 | 0.47 [0.25–0.80] | 0.005 | ||
|
| ||||||
| Owner or tenant of her/his home | 966 (82) | 604 | 0.89 [0.52–1.50] | 0.65 | ||
|
| ||||||
| Depressive symptoms (DS)b and antidepressant treatment (ADT) | ||||||
| - no DS/no ADT (ref) | 617 (52) | 421 | 1 | 1 | ||
| - no DS/ADT | 89 (7) | 76 | 1.30 [0.62–2.70] | 0.49 | 1.31 [0.64–2.71] | 0.46 |
| - DS/no ADT | 312 (26) | 238 | 1.63 [1.04–2.57] | 0.03 | 1.63 [1.04–2.54] | 0.03 |
| - DS/ADT | 172 (14) | 136 | 2.02 [1.15–3.58] | 0.02 | 1.83 [1.05–3.22] | 0.03 |
|
| ||||||
| Hazardous alcohol consumptionc | 397 (33) | 286 | 2.26 [1.49–3.42] | <10−3 | 1.91 [1.27–2.87] | 0.002 |
|
| ||||||
| Heroin used | 32 (3) | 25 | 3.79 [1.19–12.05] | 0.02 | ||
|
| ||||||
| Cocaine used | 98 (8) | 78 | 2.85 [1.43–5.67] | 0.003 | 2.26 [1.15–4.43] | 0.02 |
|
| ||||||
| Number of years since HAART initiation e | 3 [1–5] | 0.87 [0.59–1.27] | 0.46 | |||
|
| ||||||
| CDC stage C | 354 (30) | 223 | 0.68 [0.42–1.09] | 0.11 | ||
|
| ||||||
| HCV treated | 88 (7) | 0.33 [0.15–0.75] | 0.008 | 0.38 [0.17–0.84] | 0.02 | |
|
| ||||||
| Number of HAART pills per day | 4 [3–6] | 1.01 [0.92–1.09] | 0.90 | |||
|
| ||||||
| Number of symptoms* | 9 [4–14] | 1.05 [1.02–1.08] | 0.002 | - | - | |
|
| ||||||
| Daily cannabis use* | 171 (16) | 125 | 2.21 [1.21–4.06] | 0.01 | - | - |
a
Per 10-year increase
b
CES-D score>17 for men and >23 for women
c
AUDIT-C score≥4 for men and ≥3 for women
d
during the previous month
e
Per 5-year increase
*
not included in the multivariate model