Table 1.
Comparison of blood cholesterol level of rat (n=6) in MnO2 microparticles or nanoparticles (100 μg/kg) treated groups during the 14 weeks
| Days | Control | Nanoparticle | Microparticle |
|---|---|---|---|
| 0 | 69±7 | 71±6 | 66±8 |
| 2 | 71±7 | 58±5 | 54±7 |
| 4 | 68±6 | 120±9 | 87±8 |
| 6 | 67±8 | 62±5 | 82±8 |
| 8 | 69±5 | 112±8* (P=0.04) | 102±9# (P=0.0019) |
| 10 | 73±7 | 72±7 | 90±9 |
| 12 | 71±8 | 81±6 | 63±7 |
| 14 | 70±5 | 73±6 | 69±6 |
*
Control vs. Nanoparticle and microparticles groups;
#
Nanoparticles vs. Microparticle groups. Repeated measurement test showed a significant (P<0.05) difference in LDL level between groups