Table 3.

Comparison of blood LDL level of rat (n=6) in MnO2 microparticles or nanoparticles (100 μg/kg) treated groups during the 14 weeks

Days	Control	Nanoparticle	Microparticle
0	36.4±3	35.7±5	33.5±3
2	34.5±5	35±4	18±5
4	31.7±7	32±7	27±7
6	36.2±3	16.5±6* (P=0.0001)	27±3
8	38±3	45±8	18±8# (P=0.0197)
10	34±5	17±4	19±5
12	33±6	15±4* (P=0.002)	14±3
14	30±5	11±5* (P=0.002)	16±4

^*Control vs. Nanoparticle and microparticle groups;

^#Nanoparticle vs. Microparticle groups. Repeated measurement test showed a significant (P<0.05) difference in LDL level between groups