Crude and adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of all-cause mortality. HRs and 95% CIs are presented on a log2 scale, gray diamonds denote age-adjusted measures, black squares denote fully adjusted measures. Adjusting factors: all models age, diabetes, cholesterol, low- and high-density lipoprotein, smoking, hypertension; human immunodeficiency virus (HIV) viral load models additionally adjusted for CD4; CD4 models additionally adjusted for HIV viral load. Abbreviation: VACS, Veterans Aging Cohort Study.