Table 1.
Baseline Characteristics of 8168 Human Immunodeficiency Virus–Infected Veterans
| Characteristic | No AMI (n = 7972) | AMI (n = 196) | P Valuea |
|---|---|---|---|
| Age, y | 46 (40–52) | 51 (46–57) | <.0001 |
| Male sex | 7726 (96.9) | 192 (98.0) | .4014 |
| Race/ethnicity | |||
| Black/African-American | 4388 (55.0) | 90 (45.9) | .0008 |
| White | 2651 (33.3) | 89 (45.4) | |
| Hispanic | 573 (7.2) | 15 (7.7) | |
| Other | 360 (4.5) | 2 (1.0) | |
| Diabetes | 532 (6.7) | 28 (14.3) | <.0001 |
| Hypertension | 1386 (17.4) | 51 (26.0) | .0017 |
| Composite LDL and TC | |||
| LDL <130 or TC <200 | 5141 (64.5) | 93 (47.5) | <.0001 |
| LDL 130–160 or TC 200–240 | 634 (8.0) | 19 (9.7) | |
| LDL >160 or TC >240 | 209 (2.6) | 8 (4.1) | |
| Other or missing | 1988 (24.9) | 76 (38.8) | |
| HDL | |||
| HDL <40 | 3184 (39.9) | 65 (33.2) | .1442 |
| HDL ≥60 | 417 (5.2) | 10 (5.1) | |
| Other or missing | 4371 (54.8) | 121 (61.7) | |
| Smoking | |||
| Current | 4873 (61.1) | 128 (65.3) | .0098 |
| Former | 980 (12.3) | 33 (16.8) | |
| Never | 2119 (26.6) | 35 (17.9) | |
| Estimated glomerular filtration rate, mL/min/1.73 m2 | |||
| ≥60 | 6054 (75.9) | 119 (60.7) | <.0001 |
| 30–59 | 284 (3.6) | 13 (6.6) | |
| <30 | 86 (1.1) | 5 (2.6) | |
| Missing | 1548 (19.4) | 59 (30.1) | |
| Veterans Aging Cohort Study Index | |||
| <20 | 1297 (16.3) | 20 (10.2) | .0005 |
| 20–34 | 2016 (25.3) | 35 (17.9) | |
| 35–54 | 2173 (27.3) | 56 (28.6) | |
| 55+ | 2486 (31.2) | 85 (43.4) | |
| CD4 count, cells/mm3 | |||
| ≥500 | 703 (8.8) | 20 (10.2) | .0804 |
| 350–499 | 1194 (15.0) | 29 (14.8) | |
| 200–349 | 2403 (30.1) | 43 (21.9) | |
| <200 | 3672 (46.1) | 104 (53.1) | |
| Human immunodeficiency virus viral load, copies/mL | |||
| 501–999 | 216 (2.7) | 7 (3.6) | .7352 |
| 1000–9999 | 1173 (14.7) | 30 (15.3) | |
| 10 000+ | 6583 (82.6) | 159 (81.1) | |
| Hemoglobin, g/dL | |||
| ≥14 | 3049 (38.3) | 66 (33.7) | .2700 |
| 12–13.9 | 3020 (37.9) | 73 (37.2) | |
| 10–11.9 | 1383 (17.4) | 44 (22.5) | |
| <10 | 520 (6.5) | 13 (6.6) | |
| Fibrosis-4 | |||
| <1.45 | 4508 (56.6) | 98 (50.0) | .0612 |
| 1.45–3.25 | 2683 (33.7) | 70 (35.7) | |
| >3.25 | 781 (9.8) | 28 (14.3) | |
| Hepatitis C coinfection | 1742 (21.9) | 55 (28.1) | .0381 |
| AIDSb | 662 (8.3) | 18 (9.2) | .6597 |
Statistics given in median (interquartile range) or n (%).
Abbreviations: AMI, acute myocardial infarction; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TC, total cholesterol.
a Tested for significance with 2-sided Wilcoxon rank-sum and χ2 tests.
b Includes diagnosis of Kaposi's sarcoma or Pneumocystis pneumonia.