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. 2016 Nov 11;16:145. doi: 10.1186/s12890-016-0301-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Exercise-induced changes in lymphocyte subsets: Exercise caused a transient significant elevation of T lymphocytes in patients with idiopathic pulmonary arterial hypertension (IPAH) and healthy subjects (a), but not in B lymphocytes (b). In the latter, however, exercise led to a relative reduction in healthy subjects but in IPAH patients, which was not observed for absolute numbers of B lymphocytes (c and d). Exercise provoked by a non-significant trend an elevation of CD4+/CD8- T helper and CD4-/CD8+ cytotoxic T lymphocytes in patients with IPAH and healthy subjects (e and f). CD = Cluster of differentiation. ^§ p < 0.05 (t-test); ^# p < 0.05 (rANOVA)