Table 1.
Disease manifestations among the JDM cases in Cape Town
| Cumulative clinical manifestations (%) | Clinical manifestations at last review | |
|---|---|---|
| Skin | ||
| Calcinosis | 11 (44) | 8 (32) |
| Skin ulcers | 11 (44) | 1 |
| Oedema (Generalized, Periorbital or limb) | 11 (44) | 0 |
| Alopecia | 3 (12) | 3 (12) |
| Lipodystrophy | 1 (4) | 1 (4) |
| Musculoskeletal | 7 (28) | |
| Muscle tenderness | 13 (52) | 0 |
| Arthritis | 7 (28) | 2 (8) |
| Contractures | 5 (20) | 5 (20) |
| Osteoporosis with fracture | 1 (4) | 1 (4) |
| Endocrine | 9 (36) | 9 (36) |
| Growth failure | 8 (32) | 8 (32) |
| Diabetes mellitus | 1 (4) | 1 (4) |
| Adrenal insufficiency | 1 (4) | 0 |
| Respiratory | 3 (12) | 3 (12) |
| Interstitial lung disease (ILD) | 2 (8) | 2 (8) |
| Dysphonia | 2 (8) | 0 |
| Pulmonary hemorrhage | 1 (4) | 1 (4) |
| Gastrointestinal | ||
| Dysphagia | 5 (20) | 0 |
| Abdominal pain or bleeding | 3 (12) | 0 |
| Ocular | 2 (8) | 2 (8) |
| Cataracts | 2 (8) | 2 (8) |
| Cardiovascular | ||
| Abnormal capillaroscopy | 15 (60) | NA |
| Raynaud’s phenomenon | 6 (24) | NA |
| Cardiomyopathy | 1 (4) | 0 |
| Nervous system | 3 (12) | 1 (4) |
| Seizures; neuropathy | 2 (8) | 0 |
| Sensorineural hearing loss | 1 (4) | 1 (4) |
| Infections | ||
| Fungal (skin) | 7 (28) | NA |
| Bacterial (staph aureus 2, gram negative 1) | 3 (12) | NA |
| TB | 2 (8) | NA |