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. 2016 Nov 11;6:57. doi: 10.1186/s13578-016-0122-6

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — iSAECs are genomically stable. a Cell cycle distribution of early and late passage iSAECs in log phase culture (p values were determined using Student’s t test for all bar charts). b Chromosomal count of early and late passages (P14 and P79, respectively) iSAECs using metaphase spread of colcemid arrested mitotic cells. Early passage (P18) BJ fibroblasts were used as control. Numbers in each column indicates the number of metaphase spreads analyzed. c Telomere fluorescence in situ hybridization of late passage iSAECs. A representative metaphase spread image was shown