Table 6.
Biological variables and electrocardiogram before and at the end of SBT
| P values | |||||||
|---|---|---|---|---|---|---|---|
| Baseline | At the end of SBT (except for troponin Ic, measured at 4 h) | At the end of SBT vs. baseline | Succeeded SBT vs. failed SBT at baseline | Succeeded SBT vs. failed SBT at the end of SBT | Cases with WiPO vs. cases without WiPO at baseline | Cases with WiPO vs. cases without WiPO at the end of SBT | |
| PaCO2 (mmHg) | |||||||
| Succeeded SBT (n = 155) | 37 ± 7 | 38 ± 7 | |||||
| Failed SBT (n = 124) | 40 ± 8 | 46 ± 17 | <0.01 | <0.01 | <0.01 | ||
| Cases with WiPO (n = 75) | 41 ± 9 | 50 ± 18 | <0.01 | ||||
| Cases without WiPO (n = 49) | 39 ± 7 | 41 ± 12 | 0.11 | 0.01 | |||
| PaO2 (mmHg) | |||||||
| Succeeded SBT (n = 155) | 105 ± 27 | 97 ± 37 | 0.03 | ||||
| Failed SBT (n = 124) | 96 ± 22 | 72 ± 17 | <0.01 | <0.01 | <0.01 | ||
| Cases with WiPO (n = 75) | 93 ± 17 | 71 ± 16 | <0.01 | ||||
| Cases without WiPO (n = 49) | 101 ± 27 | 74 ± 20 | <0.01 | 0.05 | 0.52 | ||
| Haemoglobin (g/dL) | |||||||
| Succeeded SBT (n = 155) | 9.9 ± 1.4 | 10.0 ± 1.5 | |||||
| Failed SBT (n = 124) | 9.4 ± 1.4 | 10.0 ± 1.5 | <0.01 | <0.01 | 0.81 | ||
| Cases with WiPO (n = 75) | 9.1 ± 1.2 | 10.2 ± 1.3 | <0.01 | ||||
| Cases without WiPO (n = 49) | 9.7 ± 1.5 | 9.5 ± 1.6 | 0.04 | 0.02 | |||
| Plasma protein concentration (g/L) | |||||||
| Succeeded SBT (n = 155) | 58 ± 11 | 59 ± 11 | 0.01 | ||||
| Failed SBT (n = 124) | 55 ± 9 | 57 ± 9 | <0.01 | 0.02 | 0.19 | ||
| Cases with WiPO (n = 75) | 53 ± 9 | 58 ± 10 | <0.01 | ||||
| Cases without WiPO (n = 49) | 58 ± 9 | 57 ± 8 | 0.00 | 0.60 | |||
| Troponin Ic (ng/mL) | |||||||
| Succeeded SBT (n = 155) | 0.07 ± 0.13 | 0.09 ± 0.06 | 0.08 | ||||
| Failed SBT (n = 124) | 0.10 ± 0.08 | 0.10 ± 0.06 | 1.00 | 0.03 | 0.17 | ||
| Cases with WiPO (n = 75) | 0.11 ± 0.08 | 0.11 ± 0.08 | 1.00 | ||||
| Cases without WiPO (n = 49) | 0.07 ± 0.10 | 0.09 ± 0.09 | 0.30 | 0.02 | 0.20 | ||
| Patients with increase in troponin Ic >0.5 ng/mL | |||||||
| Succeeded SBT (n = 155) | – | 0 (0 %) | |||||
| Failed SBT (n = 124) | – | 0 (0 %) | |||||
| Cases with WiPO (n = 75) | – | 0 (0 %) | |||||
| Cases without WiPO (n = 49) | – | 0 (0 %) | |||||
| Patients with changes in electrocardiogram | |||||||
| Succeeded SBT (n = 155) | – | 5 (3 %) | |||||
| Failed SBT (n = 124) | – | 5 (4 %) | |||||
| Cases with WiPO (n = 75) | – | 4 (5 %) | |||||
| Cases without WiPO (n = 49) | – | 1 (2 %) | |||||
Values are expressed as mean ± standard deviation or number and frequency (%)
PaO2 arterial partial pressure in oxygen , PaCO2 arterial partial pressure in carbon dioxide, SBT spontaneous breathing trial, WiPO weaning-induced pulmonary oedema