Table 4.
Univariate and multivariate analyses of miR-589-5p and other factors associated with survival (n = 40)
| DFS | OS | |||
|---|---|---|---|---|
| Variables | HR (95 % CI) | p Value | HR (95 % CI) | p Value |
| Univariate analyses | ||||
| Gender (male) | 0.935 (0.320-2.732) | 0.902 | 0.790 (0.245-2.548) | 0.693 |
| Age (≥60y) | 0.979 (0.936-1.024) | 0.349 | 1.015 (0.970-1.062) | 0.513 |
| HBsAg (positive) | 1.041 (0.277-3.916) | 0.952 | 3.165 (0.659-15.196) | 0.150 |
| AFP (high) | 1.663 (0.718-3.852) | 0.235 | 1.342 (0.530-3.396) | 0.535 |
| Vascular Invasion (positive) | 1.911 (0.666-5.480) | 0.228 | 1.052 (0.314-3.5181) | 0.935 |
| Tumer Size(≥5 cm) | 1.157 (1.057-1.266) | 0.002 | 1.190 (1.072-1.321) | 0.001 |
| Edmondson Grade (III/IV) | 4.350 (1.979-9.561) | 0.000 | 2.975 (1.335-6.631) | 0.008 |
| miR-589-5pLow | 1.269 (1.095-1.470) | 0.002 | 1.226 (1.090-1.469) | 0.002 |
| Multivariate analyses | ||||
| Tumer Size(≥5 cm) | 1.067 (0.949-1.201) | 0.279 | 1.124 (0.984-1.285) | 0.085 |
| Edmondson Grade (III/IV) | 2.800 (1.140-6.877) | 0.025 | 1.573 (0.648-3.816) | 0.317 |
| miR-589-5pLow | 1.230 (1.028-1.470) | 0.023 | 1.190 (1.002-1.414) | 0.048 |