Table 1.
Pulmonary function in patients and controls
| Average | FVC (cm3) | FVC LLN (cm3) | FVC pred (cm3) | FEV1 (cm3) | FEV1 LLN (cm3) | FEV1 pred (cm3) | FEV1%pred (%) | FEV1 / FVC | FEV1 / FVC LLN | FEV / FVC pred |
|---|---|---|---|---|---|---|---|---|---|---|
| Cases | 2.69 (0.95) | 2.87 (0.81) | 3.79 (0.81) | 1.50 (0.59) | 2.01 (0.55) | 2.78 (0.61) | 53 (14) | 0.56 (0.11) | 0.62 (0.03) | 0.73 (0.03) |
| Controls | 3.96 (0.90) | 2.77 (0.77) | 3.83 (0.77) | 3.11 (0.69) | 2.05 (0.55) | 2.82 (0.59) | 110 (9) | 0.79 (0.05) | 0.62 (0.03) | 0.74 (0.03) |
| P value | 6.3 × 10−18 | 0.42 | 0.75 | 4.0 × 10−41 | 0.62 | 0.58 | 2.5 × 10−81 | 2.5 × 10−45 | 0.24 | 0.23 |
Values in parenthesis denote standard deviations. FVC Forced vital capacity, LLN Lower limit of normal, FVC pred, predicted FVC based on age, gender and length in the population. FEV1 Forced expiratory volume in 1 s, FEV1 Predicted FEV1 based on age, gender and length in the population, FEV1%pred, FEV1 Divided by predicted FEV1 in the population, FEV1 / FVC ratio when investigated the fifth year of the evaluations. The lower limit of normal (LLN) values where calculated by subtracting 1.645 × RSD (residual standard deviation) from the predicted value (pred). FEV1%pred is the measured FEV1 value divided by the predicted value (i.e., FEV1 / FEV1pred). P values are calculated using two-sided Student’s t-test assuming equal variance. SD Standard deviation