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. 2015 Sep 23;71(12):1564–1573. doi: 10.1093/gerona/glv165

Figure 6.

Figure 6.

Water-soluble cranberry extract standardized to 4.0% PAC (WCESP) improves proteostasis in aged C elegans dependent on HSF-1. (A) WCESP supplementation increases protein solubility in 10-day-old N2 worms. (B) WCESP supplementation increases protein solubility in 10-day-old CL2006 Alzheimer’s disease (AD) worms. (C) WCESP supplementation cannot increase protein solubility in 10-day-old hsf-1 (sy441) mutant worms. Soluble proteins on the sodium dodecyl sulfate–polyacrylamide gel electrophoresis are quantified by using Image-J software. Data are expressed as mean intensity from three independent experiments. The standard errors of the mean (SEM) are shown. p value was calculated using Student’s t-test. *p < .05 when compared with controls.