Table 4.
Associations in Imputed Data Between HAI and All-Cause Mortality and CVD
| Outcome | Events/N a | HR (95% CI) Model 1 | HR (95% CI) Model 2 |
|---|---|---|---|
| All-cause mortality | |||
| HR per unit of index | 233/1,348 | 1.26 (1.17, 1.36) | 1.20 (1.07, 1.35) |
| HR per category of index | |||
| 0–2 | 51/523 | 1.00 | 1.00 |
| 3–4 | 86/526 | 1.50 (1.03, 2.19) | 1.39 (0.91, 2.13) |
| 5–6 | 72/246 | 2.70 (1.84, 3.96) | 2.27 (1.35, 3.82) |
| 7–10 | 24/53 | 3.66 (2.07, 6.45) | 2.62 (1.18, 5.82) |
| CVDb | |||
| HR per unit of index | 153/1,220 | 1.29 (1.17, 1.43) | 1.14 (0.99, 1.33) |
| HR per category of index | |||
| 0–2 | 33/498 | 1.00 | 1.00 |
| 3–4 | 64/480 | 1.85 (1.19, 2.87) | 1.49 (0.91, 2.44) |
| 5–6 | 48/207 | 3.52 (2.08, 5.95) | 2.06 (0.98, 4.33) |
| 7–10 | 8/35 | 3.02 (1.26, 7.23) | 1.68 (0.63, 4.47) |
HAI = Healthy Aging Index; CVD = cardiovascular disease; HR = hazard ratio; CI = confidence interval. Model 1 is adjusted for age, sex, physical activity index, smoking status, and body mass index. Model 2 is adjusted for the covariates in Model 1 and baseline cancer, hypertension, CVD (in all-cause mortality models), diabetes, kidney disease, and pulmonary disease.
aMean # events/N per imputation.
bCVD models exclude participants with prevalent CVD.