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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Pharmacol Res. 2016 Sep 20;113(Pt A):438–448. doi: 10.1016/j.phrs.2016.09.020

Figure 1. Chemical structures of compounds used in this study.

Figure 1

Tropolones are seven membered aromatic rings which may be functionalized. Prior known tropolones include the natural product β-thujaplicin (aka Hinokitiol) and the synthetic β-phenyl tropolone. We have developed methodologies for synthesis of α-substituted tropolones such as the naphthyl and benzodioxinyl tropolones included in this study.