Table 1.
Cell line | Time (h) | IC50 [μM]
|
|
---|---|---|---|
α-naphthyl tropolone | vorinostat | ||
Molt-4 | 72 | 0.35 | 0.33 |
Daudi | 72 | 0.92 | 0.32 |
K562 | 72 | 3.25 | 0.71 |
HuT78 | 72 | 1.36 | 0.16 |
Ba/F3 WT | 72 | 2.75 | 0.32 |
HL60 | 72 | 1.97 | 0.74 |
Molt-4 | 12 | >25 | ND |
Molt-4 | 24 | 0.99 | ND |
Molt-4 | 48 | 1.05 | ND |