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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Pharmacol Res. 2016 Sep 20;113(Pt A):438–448. doi: 10.1016/j.phrs.2016.09.020

Table 2.

Selectivity of α-naphthyl tropolone and vorinostat for malignant cells versus primary cells (n=6).

IC50 [μm]
Selectivity*
hPBMC Molt-4
α-naphthyl tropolone 4.89 0.35 13.8
vorinostat 0.86 0.33 2.6
Fold difference 5.66 1.08
*

Selectivity is the fold difference of IC50 values (hPBMC/Molt-4).