Skip to main content
. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Alzheimers Dement. 2016 May 24;12(11):1125–1131. doi: 10.1016/j.jalz.2016.04.003

Table 1.

Demographics of participating subjects, and plasma and CSF protein concentrations in diagnostic groups

Control PD AD
Subject number 106 91 106
Age*
(range)		 67.1±7.4
(51–84)		 65.0±11.1
(32–84)		 69.5±8.1
(52–84)
Sex (male:female) 1.2 (58:48) 2.5 (65:26) 1.2 (57:49)
UPDRS motor*
(range)		 - 26.3±13.8
(3–67)		 -
H&Y*
(range)		 - 2.2±0.7
(1–5)		 -
MMSE*
(range)		 29.2±1.1
(28–30)		 27.6±3.0
(18–30)		 21.3±5.7
(4–27)
Disease duration,
year*
(range)		 - 6.0±4.6
(0–21)		 4.5±2.8
(0–13)
L1CAM exosomal tau
(pg/mL plasma)*
(range)		 0.178±0.138
(0.010–0.835)		 0.260±0.452
(0.020–4.262)		 0.172±0.096
(0.003–0.584)
Plasma tau (pg/mL)*
(range)		 2.405±2.759
(0.498–29.19)		 2.660±2.872
(0.504–25.87)		 3.780±2.221
(0.602–14.42)
CSF t-tau (pg/mL)*
(range)		 56.1±25.6
(11.7–226.1)		 48.5±21.1
(18.8–136.2)		 109.3±68.0
(40.7–374.1)
CSF p-tau (pg/mL)*
(range)		 35.4±13.9
(13.4–102.4)		 29.4±12.6
(13.2–86.3)		 72.8±46.9
(19.8–250.0)
CSF Aβ42 (pg/mL)*
(range)		 327.2±153.2
(60.6–821.2)		 362.6±114.7
(104.5–637.6)		 216.8±128.5
(48.9–1021.0)
*

Mean±SD.

AD, Alzheimer disease; CSF, cerebrospinal fluid; H&Y, Hoehn & Yahr; L1CAM, L1 cell adhesion molecule; MMSE, Mini Mental State Exam; PD, Parkinson disease; UPDRS, Unified Parkinson’s Disease Rating Scale.