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Simplified scheme of the ‘role’ of Rac and the molecular switch of active Rac and inactive Rac, regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Moreover, Rac GEF reaction may proceed by competitive displacement of bound GDP by GTP through a transient intermediate of GEF (GTP-Rac-GDP) [65]. GDP guanosine diphosphate, GTP guanosine triphosphate
