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Percentage of time the plasma drug concentration is above the MIC (%fT > MIC) at 4 mg/L: Monte Carlo simulations for patients in the HAP study. a %fT > MIC determined based on the population model and actual ceftobiprole plasma concentrations (n = 52); b %fT > MIC calculated based on creatinine clearance as a covariate in the overall patient population (n = 391). MIC minimum inhibitory concentration, HAP hospital-acquired pneumonia
