Table 1.
Summary of model parameters.
| Description | Formulaic abbreviation | Prescribed value(s) | Units | Reference(s) |
|---|---|---|---|---|
| Oxygen permeability | ||||
| Islet | (αD)1 | 1.24 · 10−14 | mol/cm/mm Hg/sec | [34, 35] |
| Thrombus | (αD)2 | 2.7 · 10−14 | mol/cm/mm Hg/sec | [36] |
| Oxygen supply | ||||
| External blood P | P ext | 5–40 | mm Hg | [33] |
| Oxygen threshold | ||||
| Critical P (viability) | P C | 0.1 | mm Hg | [37, 38] |
| Critical P (function) | P ∗ | 5–15 | mm Hg | [31, 34, 39–41] |
| Fractional viability | ||||
| Islet | OCR/DNA | 100–300 | nmol/min/mg DNA | [42–44] |
| Size/thickness | ||||
| Islet diameter | 2 · R | 100–300 | µm | — |
| Thrombus thickness | δ | 100 | µm | [45–48] |
| Other | ||||
| Michaelis-Menten constant (islet OCR) | K m | 0.44 | mm Hg | [39] |