Table 4.
Multivariate analysis of long-term change in creatinine (1 year minus pre-op).
| Variable | Category | Ischaemia duration as continuous variable |
Ischaemia duration <30 min vs >30 min |
||
|---|---|---|---|---|---|
| β estimate* (95% CI) | P | β estimate† (95% CI) | P | ||
| Intercept | 0.573 (0.029, 1.117) | 0.040 | 0.654 (0.158, 1.151) | 0.012 | |
| Ischaemia duration | 1-min increase | 0.003 (−0.004, 0.009) | 0.452 | – | |
| Ischaemia duration | >30 vs ≤30 min (reference) | – | 0.021 (−0.139, 0.181) | 0.792 | |
| Ischaemia type | Warm vs cold (reference) | −0.163 (−0.321, −0.005) | 0.044 | −0.195 (−0.325, −0.065) | 0.005 |
| Creatinine 24-h after surgery minus preoperative | 1-unit increase | 0.130 (−0.132, 0.393) | 0.316 | 0.126 (−0.146, 0.399) | 0.350 |
| Tumour size (cm) | 1-cm increase | 0.004 (−0.041, 0.048) | 0.869 | 0.008 (−0.035, 0.052) | 0.697 |
| Angiotensin-converting enzyme use | Yes vs no (reference) | 0.102 (−0.038, 0.242) | 0.148 | 0.091 (−0.060, 0.242) | 0.225 |
| Body mass index | 1-unit increase | −0.008 (−0.016, 0.000) | 0.061 | −0.008 (−0.016, 0.001) | 0.067 |
| Age (years) at surgery | 1-year increase | −0.006 (−0.011, −0.001) | 0.023 | −0.006 (−0.012, −0.001) | 0.031 |
| Race/Ethnicity | White non-Hispanic vs Hispanic | 0.167 (0.036, 0.299) | 0.015 | 0.172 (0.028, 0.315) | 0.021 |
| Gender | Male vs female | −0.005 (−0.126, 0.116) | 0.929 | 0.053 (−0.116, 0.126) | 0.929 |
| Hypertension | Yes vs no (reference) | 0.085 (−0.048, 0.218) | 0.200 | 0.086 (−0.049, 0.221) | 0.202 |
| Type 2 diabetes | Yes vs no (reference) | 0.029 (−0.102, 0.160) | 0.650 | 0.033 (−0.100, 0.167) | 0.614 |
| R2 | 0.554 | 0.545 | |||
*
β estimate: estimated variable coefficient in predicting long-term change in creatinine.
†
Coefficient of determination: proportion of variation of the outcome explained by the multivariate regression model. Statistically significant P values are in bold.