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Administration of 3.2 mg/kg of morphine depressed running for about one hour in uninjured male rats. Administration of 0.32 mg/kg increased running. Administration of the same doses of morphine had no effect on wheel running in female rats. There was no significant effect of injecting 1.0 mg/kg of morphine on running in either male or female rats. Sample sizes ranged from 6 – 14 rats/condition.
