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Mechanical allodynia was assessed using the von Frey test 30 min after buprenorphine administration. Administration of buprenorphine blocked mechanical allodynia in male rats compared to saline treated control rats. There was no significant effect of injecting buprenorphine on mechanical allodynia in female rats. The same rats were tested here and in Figure 4. * indicates p<.05 from saline-treated animals.
