Proposed contemporary approach to treatment of severe bifurcation lesion (20). *, typically a large SB (>2.5 mm) supplying a large territory of myocardium with significant ostial disease extending over a long segment into the SB; **, typically a smaller SB (<2.5 mm) with focal involvement of the ostium; ***, presence of important dissection or < TIMI 3 flow in SB. SB, side branch; DES, drug-eluting stent; MB, main branch; POT, proximal optimization technique; KBPD, kissing balloon post-dilatation.