Table 1.
Demographic, clinical and laboratory characteristics of patients with or without bacterial infections
| Non-infected | Infected | P value | ||||
| n | 141 | 75 | ||||
| Gender (male/female) | 77/64 | 41/34 | NS | |||
| Age (yr) | 57.3 ± 10.7 | 58.1 ± 9.7 | NS | |||
| Child-Pugh score | 6.9 ± 1.7 | 9.3 ± 2.2 | < 0.001 | |||
| Child-Pugh stage, n (%) | ||||||
| A | 58 (41.1) | 6 (8.0) | < 0.001 | |||
| B | 65 (46.1) | 28 (37.3) | ||||
| C | 18 (12.8) | 41 (54.7) | ||||
| MELD score | 12.3 ± 4.1 | 19.1 ± 9.1 | < 0.001 | |||
| Serum bilirubin (μmol/L) | 41.4 ± 38.3 | 124.1 ± 147.4 | < 0.001 | |||
| Serum albumin (g/L) | 35.4 ± 7.1 | 28.1 ± 6.5 | < 0.001 | |||
| INR | 1.3 ± 0.2 | 1.6 ± 0.5 | < 0.001 | |||
| Serum creatinine (μmol/L) | 83.8 ± 74.3 | 131.2 ± 129.9 | < 0.001 | |||
| Ascites present, n (%) | 58 (41.1) | 59 (78.7) | < 0.001 | |||
| HCC, n (%) | 4 (2.8) | 11 (14.7) | 0.003 | |||
| Comorbidities present, n (%) | 72 (51.1) | 45 (60.0) | NS | |||
| Type of bacterial infections, n (%) | ||||||
| UTI | 25 (29.4) | |||||
| SBP | 20 (23.5) | |||||
| Pneumonia | 18 (21.2) | |||||
| SSTI | 4 (4.7) | |||||
| Miscellaneous | 18 (21.2) | |||||
| Multiple | 9 (10.6) | |||||
| Acute phase proteins, median (IQR) | ||||||
| Presepsin (pg/mL) | Overall | 477 (332-680) | 1002 (575-2149) | < 0.001 | ||
| OF absent | OF present | 710 (533-1277) | 2357 (1398-3666) | < 0.001 | ||
| CRP (mg/L) | Overall | 4.6 (1.8-8.8) | 30.1 (11.3-57.4) | < 0.001 | ||
| OF absent | OF present | 25 (9.6-40.5) | 52.2 (23.4-84) | 0.027 | ||
| PCT (μmol/L) | Overall | 0.1 (0.1-0.2) | 0.4 (0.1-1.2) | < 0.001 | ||
| OF absent | OF present | 0.2 (0.1-0.5) | 1.7 (0.6-5.3) | < 0.001 | ||
Data are presented as mean ± SD or n (%) if not otherwise indicated. CRP: C-reactive protein; HCC: Hepatocellular carcinoma; IQR: Interquartile range; INR: International normalized ratio; MELD: Model for end-stage liver disease score; NS: Non-significant; PCT: Procalcitonin; SD: Standard deviation; UTI: Urinary tract infection; SBP: Spontaneous bacterial peritonitis; SSTI: Skin and soft tissue infection.