Table 2.
Baseline characteristics of patients
| Variable | Total cohort | 28-d survivors | 28-d nonsurvivors | P value |
| (n = 264) | (n = 232) | (n = 32) | ||
| Age (yr) | 48.8 ± 9.1 | 48.6 ± 9.2 | 48.3 ± 8.1 | 0.865 |
| Men, n (%) | 204 (77.3%) | 175 (75.4%) | 29 (90.6%) | 0.070 |
| Presence of cirrhosis, n (%) | 240 (90.9%) | 208 (89.7%) | 32 (100%) | 0.092 |
| SIRS, n (%) | 76 (28.8%) | 63 (27.2%) | 13 (40.6%) | 0.144 |
| Mean blood pressure (mmHg) | 89.3 ± 15.9 | 90.1 ± 15.1 | 83.5 ± 20.0 | 0.082 |
| WBC count (× 109/L) | 9.6 ± 6.0 | 9.2 ± 5.9 | 12.0 ± 6.7 | 0.013 |
| Platelet count (× 109/L) | 109.2 ± 71.5 | 110.6 ± 72.0 | 98.7 ± 68.0 | 0.377 |
| Albumin (g/dL) | 2.7 ± 0.6 | 2.7 ± 0.5 | 2.3 ± 0.6 | < 0.0001 |
| Bilirubin (mg/dL) | 11.3 ± 8.6 | 10.3 ± 8.0 | 18.7 ± 9.7 | < 0.0001 |
| AST (U/L) | 157.7 ± 86.6 | 160.5 ± 88.4 | 137.3 ± 70.7 | 0.098 |
| ALT (U/L) | 49.9 ± 32.4 | 50.4 ± 33.3 | 46.4 ± 24.6 | 0.514 |
| GGT (U/L) | 428.4 ± 437.5 | 455.4 ± 448.4 | 236.9 ± 290.5 | 0.001 |
| Prothrombin time (s) | 18.0 ± 5.2 | 17.3 ± 3.9 | 22.8 ± 9.6 | 0.004 |
| INR | 1.7 ± 0.6 | 1.6 ± 0.4 | 2.3 ± 0.9 | 0.001 |
| Creatinine (mg/dL) | 1.2 ± 1.5 | 0.9 ± 0.7 | 2.9 ± 3.6 | 0.005 |
| Sodium (mEq/L) | 133.5 ± 6.6 | 133.8 ± 6.3 | 131.1 ± 8.2 | 0.078 |
| DF score | 38.8 ± 28.2 | 34.9 ± 21.6 | 68.4 ± 48.0 | 0.001 |
| ABIC score | 7.5 ± 1.4 | 7.3 ± 1.1 | 9.0 ± 1.9 | < 0.0001 |
| GAHS | 7.4 ± 1.5 | 7.2 ± 1.3 | 9.1 ± 1.6 | < 0.0001 |
| MELD score | 21.6 ± 6.9 | 20.3 ± 5.5 | 30.6 ± 9.1 | < 0.0001 |
| MELD-Na score | 24.3 ± 6.8 | 23.1 ± 5.9 | 32.3 ± 7.2 | < 0.0001 |
| CLIF-SOFA score | 6.8 ± 3.1 | 6.1 ± 2.1 | 11.5 ± 4.6 | < 0.0001 |
| CLIF-C OF score | 7.9 ± 2.0 | 7.4 ± 1.4 | 11.2 ± 2.9 | < 0.0001 |
Data are presented as mean ± SD or n (%). SIRS: Systemic inflammatory response syndrome; WBC: White blood cell; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; GGT: Gamma-glutamyltransferase; INR: International normalized ratio; DF: Discriminant function; ABIC: Age, bilirubin, INR, creatinine; GAHS: Glasgow Alcoholic Hepatitis Score; MELD: Model for end-stage liver disease; MELD-Na: Modified MELD including sodium; CLIF-SOFA: Chronic Liver Failure-Sequential Organ Failure Assessment; CLIF-C OF: Chronic Liver Failure Consortium Organ Failure.