Fig. 1.
Areas of correlation between cortical quantitative T2* and cognitive index in multiple sclerosis. Overlay of the general linear model (GLM) significance maps (p < 0.05 corrected for multiple comparisons) showing clusters with a positive (red yellow) or negative (blue) correlation between q-T2* at 25%, 50%, and 75% depth from the pial surface and cognitive impairment as measured by the cognitive index (CI) in MS subjects.
A) Covariates of no interest included in the model were age, gender, education and cortical thickness at the vertex level.
B) Covariates of no interest included in the model were age, gender, education, cortical thickness at the vertex level and white matter lesion volume. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)