Subject area	Cancer Research
More specific subject area	Signal transduction AND Receptor Tyrosine Kinases
Type of data	Western blot; qPCR, FACS, micro-array, Computational modeling
How data was acquired	Fusion-FX7 chemiluminescence detection device (Vilber) for Western blotting,
	CLARIOstar microplate reader (BMG LABTECH) for fluorescence measurements of cell viability
	GeneChip Human Gene ST 2.0 arrays (Affymetrix) for micro-array
	FACS CantoII Instrument (Becton Dickinson, Heidelberg, Germany) for flow cytometry
	Model building and refinement with CHARMM
Experimental features	KIT and PDGFRA mutants were expressed in hek293 cell lines upon doxycycline addition
	Experiments were performed with/without ligand induction
Data source location	LIH, Luxembourg and university of Luxembourg, Luxembourg
Data accessibility	Data are available in the article, and at ArrayExpress E-MTAB-4548