. 2016 Sep 10;59(21):9672–9685. doi: 10.1021/acs.jmedchem.6b00723

Table 10. Activity against Plasmodium Life Cycle Stages.

compd	Pf (3D7) EC₅₀ (nM)	Py liver stage EC₅₀ (nM)	Pf GAM IV–V EC₅₀ (nM)^a	Pb pokinete EC₅₀ (nM)
27	4	18	104	5
30	6	1	39	14
2	1	1^b	24	5^b
38	4	4	152	15

Run in duplicate. Reference controls: pyronaridine EC₅₀ = 3108 nM, tafenoquine EC₅₀ = 5250 nM, artemisinin EC₅₀ = 0.8 nM.

Data reported previously.⁵