Table 4. SAR Study of the R3 Substituent: Aromatic Groups.
a
Calculated pKa using ChemAxon software. Experimental pKa using potentiometric titration is shown in parentheses.
b
Data for this compound reported previously.5
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.