Table 8. In vivo Oral Activity in the P. berghei Mouse Model Peter’s Test.

	4 × 30 mg/kg			4 × 10 mg/kg			4 × 3 mg/kg			4 × 1 mg/kg
compd	activity (%)	survival (days)	cure	activity (%)	survival (days)	cure	activity (%)	survival (days)	cure	activity (%)	survival (days)	cure
25	93.0	7
27	99.8	22	1/3	99.7	15		96.0	9		48.0	6.0
30	99.9	10		99.9	8		98.0	6		90.0	7
2	99.9	>30	3/3	99.9	>30	3/3	99.9	25	2/3	99.9	14
40										99.8	11.0
41										99.9	14
43										99.0	7
44										<40
49				99.1	20.3	1/3	99.2	9.3