Figure 1.

Phenotypical analysis and cytokine production of Vγ9Vδ2T cells from peripheral blood and synovial fluid of psoriatic arthritis (PsA) patients. (a) Percentages of total Vγ9Vδ2 T cells, their naive (T_naive) (CD45RA⁺CD27⁺), T central memory (T_CM) (CD45R⁻CD27⁺), T effector memory (T_EM) (CD45RA⁻CD27⁻), effector memory terminally differentiated (T_EMRA) (CD45RA⁺CD27⁻) subsets and correlation between percentage of Vγ9Vδ2 T_EM subset and disease activity index (BASDAI and DAS28). (b) Mean percentage of interferon (IFN)‐γ‐ and interleukin (IL)‐17‐producing Vγ9Vδ2 T cells. (c) Dot‐plot analysis and gating strategy of one representative PsA patient and one control [healthy donor (HD)]. (d) Percentages of total synovial fluid (SF) Vγ9Vδ2 T cells and mean percentage of Vγ9Vδ2 T cells subsets from PsA patients and controls [osteoarthritis (OA)]. Data are expressed as mean [standard error of the mean (s.e.m.)]. *P < 0·05. [Colour figure can be viewed at wileyonlinelibrary.com]