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. 2016 Oct 4;186(3):292–303. doi: 10.1111/cei.12857

Figure 1.

Figure 1

Serum lipid profiles and apolipoprotein E (ApoE) levels in ApoE mutant mice during collagen type II‐induced arthritis (CIA) development. (a) Serum levels of ApoE in B10.RIII.wild‐type (WT), B10.RIII.ApoE +/– and B10.RIII.ApoE –/– mice before (NI) and 8 weeks after (Imm) induction of CIA determined by enzyme‐linked immunosorbent assay (ELISA). (b) Serum levels of total cholesterol, high‐density lipoprotein cholesterol (HDLc), very low‐density lipoprotein/low‐density lipoprotein cholesterol (VLDL/LDLc) and triglycerides in B10.RIII.wild‐type (WT), B10.RIII.ApoE +/– and B10.RIII.ApoE –/– mice before (NI) and 8 weeks after (Imm) induction of CIA. Representative results of three independent experiments are expressed as the mean ± standard deviation (eight to 10 animals/group). Statistical differences are indicated as follows: ***P < 0·005.