Table 2.
Cardiovascular disease risk factors comparing boys and girls
| Variable | Boys (n=411) | Girls (n=270) | P Value |
|---|---|---|---|
| Systolic BP z-score | 0.39 [−0.3, 1.03] | 0.17 [−0.62, 0.92] | 0.05 |
| Diastolic BP z-score | 0.59 [−0.05, 1.16] | 0.30 [−0.26, 1.0] | 0.001 |
| Uncontrolled hypertension | 38 (155) | 26 (69) | 0.001 |
| Elevated ambulatory systolic BP | 45 (121) | 39 (72) | 0.25 |
| Elevated ambulatory diastolic BP | 42 (113) | 40 (73) | 0.70 |
| Ambulatory hypertension | 54 (146) | 48 (88) | 0.21 |
| Antihypertensive therapy | 59 (243) | 69 (185) | 0.02 |
| Angiotensin-converting enzyme inhibitor therapy | 44 (182) | 57 (154) | 0.001 |
| Angiotensin receptor blocker therapy | 9 (38) | 10 (27) | 0.79 |
| Calcium channel blocker | 13 (54) | 13 (35) | 1.00 |
| >1 antihypertensive medication | 14 (59) | 18 (48) | 0.24 |
| High phosphorous | 9 (39) | 7 (18) | 0.21 |
| Hemoglobin, g/dl | 12.8 [11.8, 13.8] | 12.4 [11.6, 13.4] | 0.01 |
| Total cholesterol, mg/dl | 169 [147, 191] | 173 [150, 197] | 0.25 |
| High total cholesterol | 25 (98) | 21 (57) | 0.35 |
| HDL cholesterol, mg/dl | 49 [40, 58] | 50 [42, 59] | 0.23 |
| Low HDL cholesterol | 12 (47) | 9 (25) | 0.37 |
| LDL cholesterol, mg/dl | 96 [74, 114] | 98 [81, 117] | 0.14 |
| High LDL cholesterol | 12 (47) | 11 (30) | 0.90 |
| Triglycerides, mg/dl | 101 [70, 150] | 98 [73, 141] | 0.96 |
| High triglycerides | 47 (187) | 38 (101) | 0.03 |
| Vitamin D-1,25 DOH | 33.6 [25.4, 42.4] | 30.4 [23.5, 38.6] | 0.01 |
| Vitamin D-25 OH | 28.3 [21.1, 35.5] | 28.3 [19.7, 35.7] | 0.73 |
| Plasma FGF23, RU/ml | 127.4 [81.2, 217.9] | 144.4 [91.4, 186.8] | 0.38 |
| Number of echocardiographic studies | 0.44 | ||
| 1 study | 52 (213) | 47 (127) | |
| 2 studies | 26 (105) | 27 (73) | |
| ≥3 studies | 23 (93) | 26 (70) | |
| LVMI at visit 2, g/m2.7 | 31.6 [26.1, 37.8] | 29.9 [25.0, 37.1] | 0.23 |
| LVMI at visit 4, g/m2.7 | 31.2 [26.7, 36.2] | 30.3 [24.2, 35.1] | 0.05 |
| LVMI at visit 6, g/m2.7 | 26.1 [21.5, 32.5] | 26.9 [22.3, 32.5] | 0.60 |
Continuous variables expressed as median [interquartile range]. Categorical variables expressed as percentage (number of subjects). Vitamin D-1,25 DOH, 1,25-dihydroxyvitamin D; Vitamin D-25 OH, 25-hydroxyvitamin D; FGF23, fibroblast growth factor 23; LVMI, left ventricular mass index.