Table 1.
Characteristics of the 15 studies contributing to the complete CIRCORT dataset.
| Study ID |
Population | Country | No. of participants (days per participant) |
Age in years (mean, range) |
% Male |
Mean time of awakening |
Samples (n) |
Assay | Sampling scheme | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Children | USA | 111 (1.9) | 3.8 (3.2–4.5) | 45% | 07:36 | 804 | DELFIA | AW30, 11, 16, BT | – |
| 2 | Children | USA | 170 (1.9) | 4.3 (0.5–7) | 52% | 07:57 | 1.222 | DELFIA | AW, 10, 16, BT | – |
| 3 | School children | Netherlands | 96 (1.9) | 9.1 (8.9–11.4) | 53% | 07:01 | 830 | IBL | AW, AW15, AW30, AW45, 12:00 |
– |
| 4 | Children. population sample | Netherlands | 1.758 (1.0) | 11.1 (10–12) | 49% | 07:00 | 5.119 | IBL | AW, AW30, 20:00 | TRAILS (Rosmalen et al., 2005) |
| 5 | School children | Netherlands | 160 (1.8) | 12 (12–12) | 49% | 07:27 | 1.022 | DELFIA | AW, AW15, AW30, AW45, 12:00, 20:00 |
NTR (Bartels et al., 2003) |
| 6 | Adolescents | Netherlands | 326 (2.9) | 17.1 (16.1–18.3) | 27% | 06:49 | 5.256 | IBL | AW, AW30, 9:30, 15:00, 19:00, 22:00 |
NTR (Kupper et al., 2005) |
| 7 | Adolescents | Netherlands | 159 (1.8) | 18.2 (17.7–19.0) | 45% | 07:45 | 1.383 | IBL | AW, AW15, AW30, AW45, 12:00 |
– |
| 8 | Students | Switzerland | 152 (3.9) | 27.2 (22–48) | 66% | 07:01 | 2.666 | DELFIA | AW, AW30, 17:00, 18:00, 18:30 |
– |
| 9 | Adults. industrial employees | Germany | 731 (3.7) | 41.7 (16–63) | 90% | 05:57 | 17.774 | IBL | AW, AW30, 8:00, 11:00, 15:00, 20:00, S15, S45 |
– |
| 10 | Adults. birth cohort | UK | 6.081 (1.0) | 45.2 (44.3–47.6) | 48% | 07:21 | 11.857 | IBL | AW45, 11:15 | British Birth Cohort (Power et al., 2008) |
| 11 | Adults. industrial employees | Germany | 539 (1.9) | 45.4 (20–71) | 88% | 05:22 | 3.276 | IBL | 11:00, 13:00, 18:00, 22:00, S15 / AW, AW30, 8:00 |
– |
| 12 | Adults. nationwide | USA | 1.138 (3.9) | 57.6 (33–84) | 45% | 06:39 | 16.980 | IBL | AW, AW30, 12:00, BT | MIDUS (Karlamangla et al., 2013) |
| 13 | Adults | Germany | 1.128 (1.0) | 60.1 (49–72) | 48% | 07:42 | 4.244 | IBL | AW, AW30, 12:00, BT | KORA (Lederbogen et al., 2010) |
| 14 | Adults. civil servants | UK | 4.148 (1.0) | 61.1 (50.5–73.9) | 73% | 06:43 | 24.454 | IBL | AW, AW30, 9:30, 15:00, 19:00, 22:45 |
Whitehall II (Badrick et al., 2007) |
| 15 | Retirees | Netherlands | 2.001 (1.0) | 75.0 (65.2–98.5) | 43% | 07:33 | 7.766 | IBL | AW, AW30, 17:00, BT | Rotterdam Study (Hofman et al., 2007) |
| Total | 18.698 (1.4) | 48.3 (8.9–98.5) | 61% | 06:47 | 104.623 | |||||
Note. Abbreviations in the sampling scheme column: AW = awakening sample. AW15-AW45 = 15. 30 or 45 min after awakening. BT = bedtime. S15 = 15 after stressor onset. S45 = 45 minutes after stressor onset. BS = beginning of working shift. numbers indicate the intended sampling time.