Extended Data Figure 8. Restoration of leg locomotor movements during overground locomotion after the spinal cord lesion.

(a) Representative sequences of locomotion along a straight corridor without stimulation and during brain-controlled stimulation recorded at 7 days and 13 days after the lesion for monkey Q2. Conventions are the same as in Figure 4. The bar plots report the mean step height of the right (lesioned) leg during swing. *, p<0.05, Wilcoxon rank sum test. Error bar, s.e.m. (b). Snapshots extracted from video recordings showing a representative sequence of leg movements during one gait cycle without stimulation and during brain-controlled stimulation at 7 days post-injury for monkey Q2. The stick diagrams overlying the right (lesioned side) leg and the trajectory of the foot are color-coded using the same color scheme as the stick diagram decomposition in panel a. Without stimulation, the monkey dragged the leg along the ground, whereas brain-controlled stimulation restored weight-bearing locomotion with plantar placement.