Figure 1. Case-control association plot for lung adenocarcinoma, LD map and regional plot of the genomic structure of the TP63 region in chromosome 3q28.
−log10 P values (y-axis) of the SNPs are shown according to their chromosomal position (x-axis). The genotyped and imputed SNPs are labelled by diamonds and circles respectively. The colour intensity of each symbol reflects the extent of LD with rs17429138: black (r2>0.8) through to white (r2<0.2). Genetic recombination rates (cM/Mb), estimated using HapMap CEU samples, are shown with a light grey line. Physical positions are based on NCBI build 36 of the human genome. Also shown are the relative position of transcripts mapping to the region.