Table 4. Smoking intensity and dependence by TP63 genotype.
Lung adenocarcinoma | Control subjects | |||||
---|---|---|---|---|---|---|
Genotype | n | Mean CPD | P-value* | n | Mean CPD | P-value* |
rs17429138 | ||||||
AA† | 358 | 19.4 | 347 | 17.7 | ||
AG | 377 | 19.0 | 425 | 18.8 | ||
GG | 94 | 19.5 | 121 | 18.6 | ||
0.99 | 0.62 | |||||
rs10937405 | ||||||
GG† | 301 | 19.9 | 288 | 17.5 | ||
AG | 405 | 18.9 | 441 | 19.1 | ||
AA | 127 | 18.4 | 165 | 17.6 | ||
0.55 | 0.07 | |||||
rs4396880 | ||||||
GG† | 345 | 19.7 | 333 | 18.3 | ||
AG | 387 | 18.8 | 435 | 18.7 | ||
AA | 106 | 18.8 | 139 | 17.2 | ||
0.44 | 0.13 |
CPD: cigarette per day
From Kruskal-Wallis test
Risk genotype