Table 4.

Twenty most significant education‐SNP interactions computed via the extended SPUR method

Marginal					Correlation
LR q‐value: 0.000232					LR q‐value: 0.03673
dbSNP ID	Associated gene	${\widehat{\beta }}_{GE}$	P‐value	FDR	dbSNP ID	${\widehat{\beta }}_{GE}$	P‐value	FDR
rs2346567_G	LOC105373456	2.13	0.000731	0.0323	rs17586724_C	0.381	0.00705	0.239
rs7805350_T	FAM188B	2.35	0.00115	0.0323	rs1052242_T	0.315	0.0105	0.239
rs2075650_G	TOMM40	−1.33	0.00403	0.0705	rs4349644_G	−0.267	0.0147	0.239
rs573399_A	TXNL1	−1.26	0.00949	0.0771	rs4869558_T	−0.259	0.0227	0.266
rs11726692_G	RNF150	1.48	0.0102	0.0771	rs4779674_A	−0.336	0.0345	0.29
rs10070086_G	GRIA1	1.4	0.0118	0.0771	rs1229658_A	−0.33	0.039	0.29
rs1530241_A	SULF1	−0.791	0.0127	0.0771	rs10924293_G	−0.274	0.0602	0.377
rs2861545_G	SPATA13	−0.976	0.0132	0.0771	rs12822144_A	0.203	0.089	0.432
rs917924_T	Intergenic	−0.9	0.0187	0.0934	rs12679472_C	0.228	0.0907	0.432
	(LOC100288868, RPL21P46)
rs7216013_A	Intergenic	1.62	0.0204	0.0934	rs9394169_A	−0.18	0.117	0.497
	(LOC100128712, MIR633)
rs17027976_G	‐	−1.14	0.0269	0.106	rs2055407_A	0.207	0.138	0.524
rs12046563_G	PPIH	−0.851	0.0292	0.106	rs9294723_A	0.159	0.15	0.524
rs7330772_T	LOC101927437	0.839	0.0305	0.106	rs1929820_T	0.154	0.165	0.529
rs2249508_C	‐	0.643	0.0363	0.116	rs10513055_C	−0.17	0.198	0.532
rs9979680_G	‐	0.989	0.0418	0.124	rs6041429_T	0.154	0.205	0.532
rs2254595_G	FAM3C	−0.535	0.0545	0.149	rs1424976_T	−0.202	0.206	0.532
rs7574256_G	‐	0.758	0.0573	0.149	rs2119380_C	−0.14	0.234	0.562
rs10494515_A	AXDND1	0.497	0.093	0.219	rs2305252_A	−0.148	0.256	0.562
rs9595108_A	‐	0.746	0.0966	0.219	rs10177104_A	−0.137	0.261	0.562
rs4747019_A	LRRC20	0.58	0.0996	0.219	rs9681094_T	−0.123	0.321	0.63

SNPs with published associations in NHGRI‐EBI GWAS Catalog (Welter et al., 2014) are marked in bold. Genes associated with significant education‐SNP interactions, at $q\le 0.1$, that have a plausible AD association are marked in bold.