Table 1.
Baseline demographics and clinical characteristics
| All patients (n = 731) | Patients with PsA (n = 217) | |
|---|---|---|
| Age, mean (SD), years | 50.7 ± 13.4 | 47.9 ± 12.0 |
| Male sex, n (%) | 556 (76.1%) | 146 (67.3%) |
| Bodyweight (kg) | 68.9 ± 15.3 | 67.0 ± 15.7 |
| BMI, mean (SD), kg/m2 | 24.8 ± 4.7 | 24.2 ± 4.7 |
| Involved BSA, mean (SD), % | 27.4 ± 22.9 | 24.0 ± 24.6 |
| Disease duration, mean (SD), years | 15.0 ± 9.8 | 13.3 ± 9.8 |
| PASI score, mean (SD) | 15.45 ± 12.21 | 13.16 ± 13.20 |
| Complications, n (%) | 431 (59.1) | 140 (64.8) |
| Past illness, n (%) | 139 (19.1)† | 42 (19.4) |
| History of tobacco use, n (%) | 353 (53.7)* | 92 (46.5)** |
| Current smoker | 227 (34.6) | 56 (28.3) |
| Previous smoker | 126 (19.2) | 36 (18.2) |
| Pretreatment drug, n (%) | ||
| Yes | 717/730 (98.2)‡ | 211/216 (97.7)§ |
| Cyclosporin | 268/730 (36.7%) | 70/216 (32.3%) |
| Vitamin D | 541/730 (74.0%) | 142/216 (65.4%) |
| Corticosteroids | 586/730 (80.2%) | 160/216 (73.7%) |
| Topical corticosteroid | 548/730 (75.0%) | 127/216 (58.5%) |
| Oral corticosteroid | 8/730 (1.1%) | 8/216 (3.7%) |
| Topical and oral corticosteroid | 29/730 (4.0%) | 24/216 (11.1%) |
| Biologic | 144/730 (19.7%) | 45/216 (20.7%) |
| Methotrexate | 81/730 (11.1%) | 73/216 (33.6%) |
| Retinoid | 80/730 (10.9%) | 27/216 (12.4%) |
| Phototherapy | 287/730 (39.3%) | 59/216 (27.2%) |
| Concomitant drug, n (%) | ||
| Yes | 592/724 (81.8%)¶ | 180/210 (85.7%)†† |
| Cyclosporin | 36/724 (4.9%) | 15/210 (6.9%) |
| Vitamin D | 360/724 (49.2%) | 83/210 (38.2%) |
| Corticosteroids | 441/724 (60.3%) | 116/210 (53.5%) |
| Topical corticosteroid | 399/724 (54.6%) | 89/210 (41.0%) |
| Oral corticosteroid | 18/724 (2.5%) | 15/210 (6.9%) |
| Topical and oral corticosteroid | 20/724 (2.7%) | 11/210 (5.1%) |
| Methotrexate | 68/724 (9.3%) | 65/210 (30.0%) |
| Retinoid | 19/724 (2.6%) | 10/210 (4.6%) |
| Phototherapy | 10/724 (1.4%) | 0/210 (0%) |
†Unknown in five patients, so the population is n = 726. *Unknown in 74 patients, so the population is n = 657. **Unknown in 19 patients, so the population is n = 198. ‡Unknown in one patient, so the population is n = 730. §Unknown in one patient, so the population is n = 216. ¶Unknown in seven patients, so the population is n = 724. ††Unknown in seven patients, so the population is n = 210. Percentages were calculated using only observed data. BMI, body mass index; BSA, body surface area; PASI, Psoriasis Area and Severity Index; PsA, psoriatic arthritis; SD, standard deviation; TNF, tumor necrosis factor.