Table 2.

Pharmacokinetic parameters of 25-OCH₃-PPD and complex in rats after oral administration

Parameters	25-OCH3-PPD	25-OCH3-PPD-phospholipid
t1/2 (hours)	2.51±0.74	3.58±0.34
Tmax (hours)	2.25±2.47	2.10±0.55
Cmax (ng/mL)	7.18±3.39	28.07±19.52*
AUC(0–24 h) (ng/mL hours)	26.65±7.11	97.24±40.17*
AUC(0–∞) (ng/mL hours)	44.52±16.40	114.02±44.84

Notes: Data are presented as mean ± SD (n=5),

^*P<0.05.

Abbreviations: AUC, area under the curve; SD, standard deviation.