. Author manuscript; available in PMC: 2017 Oct 1.

Published in final edited form as: Alcohol Clin Exp Res. 2016 Sep 21;40(10):2102–2113. doi: 10.1111/acer.13206

Table 2.

Effect of ethanol on novelty-seeking behaviors in HIV-1Tg and F344 rats as measured by hole-board and open field tests.

Behavioral Test	Behaviors	HIV-1Tg			F344
Behavioral Test	Behaviors	Pre-treatment (Mean ± SEM)	Post-treatment (Mean ± SEM)	P-value	Pre-treatment (Mean ± SEM)	Post-treatment (Mean ± SEM)	P-value
Hole-Board Test	Head Dip	30.61 ± 1.74	53.77 ± 2.9	5.19 × 10⁻⁶	22.62 ± 1.30	32.69 ±2.38	0.0011
	Rearing	4.42 ± 1.33	3.07 ± 0.95	0.09	7.06 ± 1.38	5.04 ±1.00	0.07
	Grooming	3.55 ± 0.53	4.13 ± 0.49	0.43	3.885 ± 0.52	3.61 ± 0.93	0.80
	Time mobile	301.5 ± 14.37	251.6 ± 21.65	0.07	286.7 ± 26.48	228.6 ±14.53	0.06
Open Field Test	Center entry	23.78 ± 3.00	46.00 ± 2.88	1.64 x10⁻⁵	14.85 ± 1.78	24.62 ±2.56	0.004
	Center time	47.59 ± 8.31	126.9 ± 10.09	6.71 × 10⁻⁵	26.75 ± 5.78	61.95 ±9.74	0.004
	Time mobile	282.8 ± 20.53	274.6 ± 16.52	0.76	288.8 ± 25.85	210.1 ±15.47	0.015