Table 4.

Organ weight-to-body weight ratio of female BALB/c mice after treatment with TQ and TQNLC in the acute toxicity study

Group	Liver	Spleen	Lungs	Heart	Kidneys
Control	4.67±0.39	0.40±0.11	0.51±0.01	0.41±0.07	1.15±0.05
Blank NLC	4.59±0.08	0.42±0.05	0.69±0.05	0.45±0.12	1.13±0.03
Olive oil	4.58±0.73	0.43±0.03	0.59±0.01	0.38±0.05	1.08±0.06
TQNLC
5 mg/kg	5.42±0.28	0.49±0.07	0.73±0.07	0.48±0.08	1.00±0.36
50 mg/kg	4.93±0.05	0.53±0.02	0.58±0.03	0.43±0.04	1.08±0.04
300 ms/kg	4.83±0.19	0.41±0.03	0.66±0.14	0.46±0.08	1.27±0.14
TQ
5 mg/kg	4.81±0.41	0.42±0.09	0.63±0.15	0.51±0.09	1.23±0.08
50 mg/kg	4.41±0.27	0.42±0.05	0.74±0.06	0.46±0.03	1.13±0.13

Note: Values are expressed as mean ± SEM, n=3.

Abbreviations: NLC, nanostructured lipid carrier; TQ, thymoquinone; TQNLC, TQ-loaded NLC; SEM, standard error of measure.