Table S3.
Vaginal irritation scores for four groups
| Group | Epithelium
|
Mucosa
|
Score | Mean ± SD | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Intact
|
Partial exfoliation
|
Exudation
|
Vascular congestion
|
Edema
|
Leukocyte infiltration
|
|||||||||
| 0 | 1 | 2 | Obvious
|
Medium
|
Mild
|
Obvious
|
Medium
|
Mild
|
Obvious
|
Medium
|
Mild
|
|||
| 3 | 2 | 1 | 3 | 2 | 1 | 3 | 2 | 1 | ||||||
| 1-1 | √ | √ | √ | √ | 7 | 6.0±1.0 | ||||||||
| 1-2 | √ | √ | √ | √ | 5 | |||||||||
| 1-3 | √ | √ | √ | √ | 6 | |||||||||
| 2-1 | √ | √ | √ | √ | 5 | 4.7±0.6 | ||||||||
| 2-2 | √ | √ | √ | √ | 5 | |||||||||
| 2-3 | √ | √ | √ | √ | 4 | |||||||||
| 3-1 | √ | √ | √ | √ | 5 | 4.7±0.6 | ||||||||
| 3-2 | √ | √ | √ | √ | 4 | |||||||||
| 3-3 | √ | √ | √ | √ | 5 | |||||||||
| 4-1 | √ | √ | √ | √ | 4 | 4.3±0.6 | ||||||||
| 4-2 | √ | √ | √ | √ | 4 | |||||||||
| 4-3 | √ | √ | √ | √ | 5 | |||||||||
Notes: Group 1: normal saline; Group 2: IFN; Group 3: PBNP-S; Group 4: IFN-loaded PBNP-S. 0, 1, 2 and 3 mentioned in the column head refer to score.
Abbreviations: PBNP-S, sulfonate-modified phenylboronic acid-rich nanoparticles; IFN, interferon; SD, standard deviation.