Table 3.
Serial changes in HBV-DNA levels and liver function for propensity score-matched patients
| Variable | LAM group | ADV group | P-value |
|---|---|---|---|
| HBV-DNA (log10 IU/mL) | |||
| Baseline | 5.2 (2.7–6.0) | 4.7 (2.7–5.7) | 0.364 |
| 1 year after resection | 2.7 (1.4–4.7) | 3.0 (2.1–4.7) | 0.012 |
| 2 years after resection | 2.4 (1.8–4.1) | 2.7 (1.2–3.8) | 0.876 |
| 3 years after resection | 2.1 (1.0–3.6) | 2.3 (1.1–2.7) | 0.180 |
| Total bilirubin (μmol/L) | |||
| Baseline | 13.8±9.0 | 14.0±7.5 | 0.940 |
| 1 year after resection | 13.0±8.0 | 14.1±5.4 | 0.706 |
| 2 years after resection | 13.9±8.5 | 13.9±7.9 | 0.598 |
| 3 years after resection | 11.2±5.1 | 13.4±4.1 | 0.335 |
| Albumin (g/L) | |||
| Baseline | 41.2±4.4 | 41.3±4.3 | 0.922 |
| 1 year after resection | 43.4±4.0 | 43.0±5.0 | 0.720 |
| 2 years after resection | 43.0±4.6 | 45.4±4.3 | 0.133 |
| 3 years after resection | 42.5±4.3 | 42.5±6.4 | 0.999 |
| Alanine aminotransferase (IU/L) | |||
| Baseline | 37.5 (8.0–192.0) | 36.5 (5.0–109.0) | 0.575 |
| 1 year after resection | 30.0 (12.0–158.0) | 34.0 (13.0–82.0) | 0.002 |
| 2 years after resection | 22.0 (11.0–103.0) | 28.0 (16.0–78.0) | 0.325 |
| 3 years after resection | 26.0 (6.0–159.0) | 29.0 (21.0–137.0) | 0.680 |
| Prothrombin time (s) | |||
| Baseline | 12.9±1.5 | 13.0±1.1 | 0.875 |
| 1 year after resection | 13.3±1.4 | 13.3±1.5 | 0.863 |
| 2 years after resection | 13.1±1.3 | 13.4±1.6 | 0.539 |
| 3 years after resection | 13.0±1.2 | 13.2±1.5 | 0.764 |
Note: Variables are expressed as mean ± standard deviation or as median (range).
Abbreviations: ADV, adefovir dipivoxil; LAM, lamivudine; HBV, hepatitis B virus; s, seconds.