Table 1.
Characteristics (n, %) | No Empiric TB Treatment (n=505) | Empiric TB Treatment (n=126) | p-Value |
---|---|---|---|
Women | 296 (59) | 70 (56) | 0.53 |
Median age (IQR), years | 33 (28-40) | 32 (28-39) | 0.36 |
Median CD4+ count (IQR), cells/μL | 72 (20-205) | 86 (26-207) | 0.44 |
Antiretroviral therapy on admission | 113 (22) | 20 (16) | 0.11 |
CTX prophylaxis | 275 (54) | 72 (57) | 0.59 |
Antibiotics for current illness | 307 (61) | 74 (59) | 0.67 |
Productive cough | 459 (91) | 99 (79) | <0.001 |
Dyspnea | 298 (59) | 73 (58) | 0.83 |
Weight loss (>5 kg) | 469 (93) | 119 (94) | 0.53 |
Danger signs | 248 (49) | 74 (59) | 0.053 |
Fever (T>39°C) | 27 (5) | 13 (10) | 0.041 |
Tachycardia (HR>120) | 105 (21) | 42 (33) | 0.003 |
Tachypnea (RR>30) | 195 (39) | 49 (39) | 0.96 |
Hypoxia (SpO2≤93%) | 170 (34) | 46 (37) | 0.55 |
Chest radiograph consistent with TB | 277 (65)* | 73 (63)† | 0.78 |
Mycobacterial culture-positive | 108 (23) | 59 (52) | <0.001 |
Abbreviations: CTX, co-trimoxazole; HR, heart rate; IQR, interquartile ratio; RR, respiratory rate; SpO2, Oxygen saturation; T, Temperature; TB, tuberculosis.
Legend:
Missing 78 observations
Missing 11 observations