Table 1.
Spectrum of antimicrobial activity for JBIR-100. MICs are reported as the modal value obtained from three experiments with three independent cultures each.
| Microorganism | MIC (µM) |
|---|---|
| Firmicutes (Gram-positive) | |
| Bacillus anthracis Sterne ΔLF | 4 |
| Bacillus cereus ATCC 4342 | 4 |
| Bacillus subtilis subsp. subtilis str. 168 | 8 |
| Bacillus subtilis ATCC 47096 | 8 |
| Bacillus sp. Al Hakam | 4 |
| Enterococcus faecium U503 (VRE1) | 16 |
| Staphylococcus aureus USA300 (MRSA2) | 4 |
| Actinobacterium | |
| Mycobacterium smegmatis B-14616 | > 64 |
| Proteobacteria (Gram-negative) | |
| Escherichia coli DH5α | > 64 |
| Escherichia coli MC1061 | > 64 |
| Pseudomonas putida KT2440 | > 64 |
| Ascomycota (Fungi) | |
| Candida albicans | > 128 |
| Debaryomyces hansenii | 8 |
| Kluyveromyces lactis | > 64 |
| Saccharomyces cerevisiae | > 64 |
| Zygosaccharomyces rouxii | 32 |
1
Vancomycin-resistant Enterococcus.
2
Methicillin-resistant Staphylococcus aureus